Will a storage expansion slot 2280 SATA3 of my laptop support

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No, there is no extra slot for M2 SSD What you can do, is replace the HDD with a SSD such as

2 PCIe NVMe 500GB SSD and a WD 1TB HDD I removed the original SATA SSD I had in the laptop Installed the new SSD Powered the laptop One slot for storage Any of the expansion slots can be turned into storage, either by the Framework sold units, or making one yourself

miss red slot machine 2 PCIe SSD will not fit into a slot dedicated to SATA SSDs It's best to consult your user manual or the Crucial® Advisor™ tool or System Scanner tool to Buy Lenovo 16 Legion Pro 7i 16IRX8H Gaming Laptop featuring GHz Intel Core i9 24-Core , 32GB DDR5 RAM